Noninvasive diagnosis of infection using plasma next-generation sequencing: a single-center experience
J Rossoff, S Chaudhury, M Soneji… - Open forum …, 2019 - academic.oup.com
Open forum infectious diseases, 2019•academic.oup.com
Pediatric patients frequently present with illnesses strongly suggesting infection, but without
a clearly identified etiology. Our center has recently added a commercially available plasma
metagenomic sequencing assay to its available diagnostic testing. Our experience with the
first 100 tests suggests that this technology has good clinical performance with> 90%
sensitivity.
a clearly identified etiology. Our center has recently added a commercially available plasma
metagenomic sequencing assay to its available diagnostic testing. Our experience with the
first 100 tests suggests that this technology has good clinical performance with> 90%
sensitivity.
Abstract
Pediatric patients frequently present with illnesses strongly suggesting infection, but without a clearly identified etiology. Our center has recently added a commercially available plasma metagenomic sequencing assay to its available diagnostic testing. Our experience with the first 100 tests suggests that this technology has good clinical performance with >90% sensitivity.
Oxford University Press