Characterization of the Aspergillus fumigatus chitosanase CsnB and evaluation of its potential use in serological diagnostics
J Beck, M Broniszewska, M Schwienbacher… - International Journal of …, 2014 - Elsevier
Aspergillus fumigatus is currently the major air-borne fungal pathogen as its asexual spores
are distributed through the air. In severely immunocompromised patients, inhalation of these
conidia can result in life-threatening infections. Invasive Aspergillosis, a major Aspergillus-
associated disease, is associated with a high mortality reflecting short-comings in
diagnostics and therapy. Current diagnostics largely rely on the serological detection of the
galactomannan antigen. Detection of circulating antibodies is an alternative approach. In …
are distributed through the air. In severely immunocompromised patients, inhalation of these
conidia can result in life-threatening infections. Invasive Aspergillosis, a major Aspergillus-
associated disease, is associated with a high mortality reflecting short-comings in
diagnostics and therapy. Current diagnostics largely rely on the serological detection of the
galactomannan antigen. Detection of circulating antibodies is an alternative approach. In …
