Secretome analysis of Aspergillus fumigatus reveals Asp-hemolysin as a major secreted protein

D Wartenberg, K Lapp, ID Jacobsen, HM Dahse… - International journal of …, 2011 - Elsevier
Surface-associated and secreted proteins represent primarily exposed components of
Aspergillus fumigatus during host infection. Several secreted proteins are known to be
involved in defense mechanisms or immune evasion, thus, probably contributing to
pathogenicity. Furthermore, several secreted antigens were identified as possible
biomarkers for the verification of diseases caused by Aspergillus species. Nevertheless,
there is only limited knowledge about the composition of the secretome and about molecular …