Aspergillus bronchitis in cystic fibrosis

D Shoseyov, KG Brownlee, SP Conway, E Kerem - Chest, 2006 - Elsevier
Aspergillus fumigatus, a widely distributed spore-bearing fungus, is commonly grown in
sputum cultures of patients with cystic fibrosis (CF). A fumigatus may cause allergic
bronchopulmonary aspergillosis (ABPA), a complex condition that leads to worsening of
airway inflammation and progressive damage and is diagnosed by specific criteria. In this
report, we present six CF patients with respiratory deterioration that did not respond to
appropriate antibiotic treatment. All had had A fumigatus in sputum cultures but did not fulfill …