Abstract Exosomes are small (30–150 mm) vesicles secreted by all cell types and present in
all body fluids. They are emerging as vehicles for delivery of membrane-tethered signaling
molecules and membrane enclosed genes to target cells. Exosome-mediated information
transfer allows for crosstalk of cells within the hematopoietic system and for interactions
between hematopoietic cells and local or distant tissue cells. Exosomes carry physiological
signals essential for health and participate in pathological processes, including malignant …