It is now becoming clear that the inflammatory cells that exist in the tumour
microenvironment play an indispensable role in cancer progression. Tumour associated
macrophages (TAMs) represent a prominent component of the mononuclear leukocyte
population of solid tumours, which displays an ambivalent relationship with tumours. They
originate in the circulation and are recruited to the tumour site by tumour-derived attractants
such as chemokines and interact with the tumour cells and preferentially localize at the …