Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure

R Garg, S Yusuf, WD Bussmann, P Sleight, A Uprichard… - Jama, 1995 - jamanetwork.com
Objective.—To evaluate the effect of angiotensin-converting enzyme (ACE) inhibitors on
mortality and morbidity in patients with symptomatic congestive heart failure. Data Sources
and Study Selection.—Data were obtained for all completed, published or unpublished,
randomized, placebo-controlled trials of ACE inhibitors that were at least 8 weeks in duration
and had determined total mortality by intention to treat, regardless of sample size. Trials
were identified based on literature review and correspondence with investigators and …